Daytime light exposure in daily life and depressive symptoms in bipolar disorder: a cross-sectional analysis in the APPLE cohort - Esaki Y, Kitajima T, Obayashi K, Saeki K, Fujita K, Iwata N.

This study investigated the ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Environmental Issues, Climate, Geophysics Source Type: news

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ConclusionsThe findings suggest that greater daytime light exposure in daily life is associated with decreased depressive symptoms in BD.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
AbstractPurposeIn this review, we will review the background and diagnosis of bipolar disorder (BD); describe the efficacy data and potential circadian and neural mechanisms underlying the effects of bright light for bipolar depression; and discuss the implementation of light therapy in clinical practice.Recent FindingsTo date, morning bright light is the most widely tested form of light therapy for all mood disorders. Clinical trial reports suggest that midday or morning bright light treatment and novel chronotherapeutic interventions are effective for bipolar depression. Mechanisms of response may relate to effects on th...
Source: Current Psychiatry Reports - Category: Psychiatry Source Type: research
ConclusionsPsychosocial, pharmacological, and light-based approaches are promising avenues for treating circadian dysfunction in BD.
Source: Current Psychiatry Reports - Category: Psychiatry Source Type: research
Improving outcomes in patients with depression and posttraumatic stress disorder, drug development, and psychotherapy were among the topics of the seven articlesselected as favorites of 2018 by the editors of theAmerican Journal of Psychiatry. The articles are listed below in the order they appeared in the print issue of the Journal:Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-blind Placebo-controlled Trial: Dorothy Sit, M.D., and colleagues randomly assigned adults with bipolar I or II disorder with symptoms of major depression who were on stable concomitant medications to either a 7,000-lux...
Source: Psychiatr News - Category: Psychiatry Tags: aging American Journal of Psychiatry bipolar disorder bright light therapy depression methylation propranolol psychotherapy PTSD suicide TNF- α Source Type: research
This study protocol aims to determine, using a rigorous approach in patients with bipolar disorder (BD) and non-seasonal major depressive episode (MDE), the characteristics of bright light therapy (BLT) administration (duration, escalation, morning and mid-day exposures) depending on the tolerance (hypomanic symptoms). Methods: Patients with BD I or II and treated by a mood stabilizer are eligible. After 1 week of placebo, patients are randomized between either morning or mid-day exposure for 10 weeks of active BLT with glasses using a dose escalation at 7.5, 10, 15, 30 and 45 minutes/day. A further follow-up visit is ...
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research
peli NY, Yoshiike T, Yu X PMID: 30173556 [PubMed - in process]
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research
American Journal of Psychiatry,Volume 175, Issue 9, Page 905-906, September 01, 2018.
Source: American Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research
Bipolar disorder affects women throughout their childbearing years. During the perinatal period, women with bipolar disorder are vulnerable to depressive episode recurrences and have an increased risk for postpartum psychosis. Perinatal screening is critical to identify women at risk. Although medications are the mainstay of treatment, the choice of pharmacotherapy must be made by the patient based on a risk –benefit discussion with her physician. For optimal dosing in pregnancy, therapeutic drug monitoring may be required to maintain effective drug concentrations. Residual symptoms of bipolar depression are treatabl...
Source: Obstetrics and Gynecology Clinics - Category: OBGYN Authors: Source Type: research
Authors: Cools O, Hebbrecht K, Coppens V, Roosens L, De Witte A, Morrens M, Neels H, Sabbe B Abstract INTRODUCTION: A seasonal affective disorder (SAD) is a subtype of unipolar and bipolar major depressive disorders. It is characterized by its annual recurrence of depressive episodes at a particular season, mostly seen in winter and is responsible for 10-20% of the prevalence of major depressive disorders. Some pathophysiological hypotheses, such as the phase delay and the monoamine depletion hypotheses, have been postulated but the exact cause has not been fully unraveled yet. Studies on treatment for SAD in the l...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Abstract Patient diurnal mood fluctuation, sleep characteristics and factors affecting sleep homeostasis predict antidepressant response to the combination of total sleep deprivation and light therapy (TSD + LT). In order to study if chronotype could influence response to TSD+LT, we considered 194 bipolar depressed patients. Severity of depression was rated with Hamilton Depression Rating Scale; perceived mood levels were assessed by a self-administered 10-cm visual analogue scale and chronotype was assessed using the Mornigness-Eveningness Questionnaire. More than 60% of patients resulted responders to ...
Source: Chronobiology International - Category: Biology Authors: Tags: Chronobiol Int Source Type: research
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