Work disability and musculoskeletal disease

International Journal of Rheumatic Diseases, Volume 22, Issue 6, Page 965-966, June 2019.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: EDITORIAL Source Type: research

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Conclusions: Neurocutaneous syndromes are clinically heterogeneous and the surveillance of potential clinical complications is challenging. The availability of genetic diagnosis and novel imaging methods in this group of disorders is likely to further expand their clinical spectrum. Guidelines for assessment and management will need to be modified based on new available data. PMID: 31443616 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Conclusions. The BENECA mHealth lifestyle application with a supervised rehabilitation program had a statistically and clinically significant effect on QoL and upper-limb functionality in breast cancer survivors and is a unique and important promising new approach.
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Kerry Thompson, 40, from Milton Keynes, waited more than a decade for a smear test as a result of her disability. Luckily, Kerry's results came back clear. But her story is not unique.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Lindau David Lewis Disability-disaggregated data are increasingly considered important to monitor progress in Universal Eye Health Care. Hospital-based data are still elusive because of the cultural ambiguities of the term disability, especially in under-resourced Health Information Systems in low-and middle-income countries. The aim of this study was to estimate the hospital-based rate of disability in patients presenting at an eye department of a rural hospital in Paraguay and to discuss implications for the management of access barriers. Therefore, we introduced two standardized sets of the Washington Group (WG) ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Conclusions: Interventions to promote hearing aid use need to focus on addressing reasons for the perception of hearing difficulties and how to promote hearing aid use. Interventions to promote hearing aid use may need to target demographic groups that are particularly unlikely to use hearing aids, including younger adults, those who live alone and those from ethnic minority backgrounds.
Source: Ear and Hearing - Category: Audiology Tags: Research Articles Source Type: research
Conclusion - Our studies substantiate the eligibility of mice and zebrafish models for human MCT8 deficiency. However, differences in the intrinsic transporter properties of MCT8 orthologues may exist, which should be realized when comparing MCT8 deficiency in different in vivo models. Moreover, our findings may indicate that the protein domains outside the substrate channel may play a role in substrate selection and protein stability. PMID: 31436139 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Source: American Journal of Health Behavior - Category: Psychiatry & Psychology Authors: Source Type: research
Contributors : Tomassoni-Ardori Francesco ; Skyler Kuhn ; Vishal Koparde ; Lino TessarolloSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBrain Derived Neurotrophic Factor (BDNF) is a potent modulator of brain synaptic plasticity. Signaling defects caused by dysregulation of its NTrk2 (TrkB) kinase (TrkB.FL) and truncated receptors (TrkB.T1) have been linked to the pathophysiology of several neurological and neurodegenerative disorders. We found that upregulation of Rbfox1, an RNA binding protein associated with intellectual disability, epilepsy and autism,  increases selectively...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
ConclusionsThese studies demonstrate child sleep problems are associated with poorer parent mental health and higher parenting stress.ImplicationsFuture longitudinal research including multiple measurements of child sleep problems and family functioning is required to clarify the directionality of associations. Such knowledge is key in adapting sleep interventions to better meet the needs of children with ADHD or ASD and their families.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Publication date: Available online 22 August 2019Source: Stem Cell ResearchAuthor(s): Natascia Malerba, Patrizia Benzoni, Gabriella Maria Squeo, Raffaella Milanesi, Federica Giannetti, Lynette G. Sadleir, Gemma Poke, Bartolomeo Augello, Anna Irma Croce, Andrea Barbuti, Giuseppe MerlaAbstractGNB5 loss-of-function pathogenic variant cause IDDCA, a rare autosomal recessive human genetic disease characterized by infantile onset of intellectual disability, sinus bradycardia, hypotonia, visual abnormalities, and epilepsy. We generated a human induced pluripotent stem cells (hiPSCs) from skin fibroblasts of a patient with the hom...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
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