Atraumatic and aseptic osteonecrosis of large joints.

[Atraumatic and aseptic osteonecrosis of large joints]. Radiologe. 2019 Jun 27;: Authors: Grieser T Abstract Subchondral osteonecrosis of large weight-bearing joints (hip and knee joints) represents a severe and joint-threatening disease. Apart from idiopathic forms, glucocorticoid medication and alcohol abuse have been identified as major causative factors for atraumatic osteonecrosis. In addition to direct cytotoxic factors, a critically reduced perfusion of the subchondral osseous space will eventually lead to bone marrow ischemia and osseous necrosis. Magnetic resonance imaging (MRI) is capable of visualizing a reactive border-like zone in this early, already irreversible and often asymptomatic stage I according to the Association of Research Circulation Osseous (ARCO) staging system. Later in the course, osteonecrosis progresses to form serpiginous sclerotic lines, enclosing the necrotic bone area (stage II ARCO). Repair mechanisms of osteonecrosis are mostly unsuccessful and depending on the size of the osteonecrosis result in biomechanical failure and ultimately subchondral insufficiency fractures (crescent sign), thus marking the transition to stage III ARCO (joint surface collapse). PMID: 31250028 [PubMed - as supplied by publisher]
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research

Related Links:

ConclusionQHD inhibits LPS gut-leakage in NASH, which is associated with downregulation of intestinal MAPK pathway.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
WellNow Urgent Care has opened a new site in West Seneca, it's 13th in Western New York.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
Publication date: Available online 10 November 2019Source: Materials Today CommunicationsAuthor(s): Farnaz Ghorbani, Ali Zamanian, Amir AidunAbstractPolyurethane is an important synthetic polymer which considered promising for bone tissue engineering. Besides, presence of conductive polymer such as could play a crucial role in efficient reconstruction of injured tissue. In the present study, the polyurethane-polyaniline scaffolds were fabricated by electrospinning technology. The electrospun fibers were modified by oxygen plasma treatment technique for immobilization of polyvinyl alcohol and 3-Glycidoxypropyl-trimethoxysil...
Source: Materials Today Communications - Category: Materials Science Source Type: research
This article aims to show that the terms ‘use’ and ‘abuse’ conventionally mobilized to speak of good and bad consumption are not able to exhaust the range of possibilities in terms of alcohol drinking behaviors understanding. Indeed, only the consideration of contextual and identity dynamics can allow us to understand with accuracy the relationship to this substance.Graphical abstract
Source: Current Opinion in Food Science - Category: Food Science Source Type: research
BACKGROUND: Adolescent alcohol consumption is an issue of ongoing concern and programs targeting parents have been identified as an important component in minimizing and preventing alcohol related harm in adolescents. This paper aims to evaluate existing p...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Objective: Alcohol use is implicated in 50 to 70% of campus sexual assaults (CSA). Despite research, practice, and policy guidance that campus prevention efforts should address alcohol's role in CSA, there is limited guidance for prevention educator...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Rates of co-occurring depression and alcohol use are higher among college students than in the general population. Further research is needed to illuminate how the mechanisms with which individuals process negative emotions may clarify the link between dep...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: The purpose of this study was: (a) to estimate trends over time in the prevalence of alcohol consumption among female adolescents between 2006 and 2014; (b) to identify the factors associated with the probability of consuming alcohol during thi...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: While research suggests that chronic childhood adversities may be predictors of alcohol use disorders, little is known of their influence on accelerated transitions through stages of alcohol involvement. We estimated the speed of transition fro...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: Almost a decade ago, Sweden became the first country to implement a national system enabling student health care centers across all universities to routinely administer (via email) an electronic alcohol screening and brief intervention to their...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
More News: Alcoholism | Gastroschisis Repair | MRI Scan | Orthopaedics | Perfusion | Radiology