Cellular organization of the transfer of genetic information.

Cellular organization of the transfer of genetic information.
Curr Opin Microbiol. 2013 Feb 6;
Authors: Campos M, Jacobs-Wagner C
Abstract
Each step involved in the transfer of genetic information is spatially regulated in eukaryotic cells, as transcription, translation and mRNA degradation mostly occur in distinct functional compartments (e.g., nucleus, cytoplasm and P-bodies). At first glance in bacteria, these processes seem to take place in the same compartment - the cytoplasm - because of the conspicuous absence of membrane-enclosed organelles. However, it is becoming increasingly evident that mRNA-related processes are also spatially organized inside bacterial cells, and that this organization affects cellular function. The aims of this review are to summarize the current knowledge about this organization and to consider the mechanisms and forces shaping the cell interior. The field stands at an exciting point where new technologies are making long-standing questions amenable to experimentation.
PMID: 23395479 [PubMed - as supplied by publisher]

Source: Current Opinion in Microbiology - February 6, 2013 Category: Microbiology Authors: Campos M, Jacobs-Wagner C Tags: Curr Opin Microbiol Source Type: research