Bone union after spinal fusion surgery using local bone in long-term bisphosphonate users: a prospective comparative study

ConclusionsEven though there was significant delayed union after 6  months in long-term BPs users, at the 2-year postoperative follow-up, there was no significant difference in bone fusion rate between the two groups. Long-term BPs users showed fusion rates greater than 80% and clinical outcome improvements that were comparable to those in non-users. No significan t effect on fusion rate after PLIF was found in long-term BPs users.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research