Bacteriologic profile and susceptibility pattern of mechanically ventilated paediatric patients with pneumonia

ConclusionSevere community-acquired pneumonia was treated with macrolides in combination with vancomycin or linezolid if methicillin-resistant S. aureus was suspected. This was appropriate, in view of its causative agents and their susceptibility pattern. Hospital and ventilator-associated pneumonia caused by resistant Gram-negative organisms might have better outcomes by adding tigecycline or colistin in combination with fluoroquinolones. Owing to the widespread resistance of many Gram-negative bacteria, it is recommended that the antibiotic stewardship program be frequently updated.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research