Recent Advancement and Clinical Implications of 18FDG-PET in Parkinson ’s Disease, Atypical Parkinsonisms, and Other Movement Disorders

This article reviews FDG-PET studies in Parkinson ’s disease (PD), atypical parkinsonism (AP), Huntington’s disease (HD), and dystonia.Recent FindingsThe metabolic pattern of PD, disease progression, non-motor symptoms such as fatigue, depression, apathy, impulse control disorders, and cognitive impairment, and the risk of progression to dementia have been identified with FDG-PET studies. In prodromal PD, the REM sleep behavior disorder-related covariance pattern has been described. In AP, FDG-PET studies have demonstrated to be superior to D2/D3 SPECT in differentiating PD from AP. The metabolic patterns of HD and dystonia have also been described.SummaryFDG-PET studies are an excellent tool to identify patterns of brain metabolism.
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research

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Source: Journal of Injury and Violence Research - Category: International Medicine & Public Health Source Type: research
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Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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