Patterns of response to antidepressants in major depressive disorder: drug resistance or worsening of depression are associated with a bipolar diathesis - Perugi G, Pacchiarotti I, Mainardi C, Verdolini N, Menculini G, Barbuti M, Angst J, Azorin JM, Bowden CL, Mosolov S, Young AH, Vieta E.

Resistance and worsening of depression in response to antidepressants (ADs) are major clinical challenges. In a large international sample of patients with major depressive disorder (MDD), we aim to explore the possible associations between different patte...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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Are you always in control and always perfectly put together? Are you professionally successful, a great friend, and always showing a happy face to the world?  But what about on the inside? Is there something in the background or in the past that you don’t talk about?  Do you feel disconnected, like no one knows the “real” you? Deep down do you just know something is wrong? Well, you might have “perfectly hidden depression.” Today Gabe speaks with Dr. Margaret Rutherford who has done extensive work on the relationship between perfectionism and depression.  Dr. Rutherford tells u...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Depression General Happiness Interview LifeHelper Mental Health and Wellness Perfectionism Personality Podcast Psychiatry Psychology Research Self-Esteem Self-Help The Psych Central Show Trauma Source Type: blogs
Publication date: Available online 27 September 2019Source: Brain, Behavior, and ImmunityAuthor(s): Jane Pei-Chen Chang, Kuan-Pin SuAbstractThe ‘monoamine hypothesis’ is insufficient in approaching the aetiology of psychiatric disorders or in developing novel therapies. Accumulating evidence suggests that inflammatory regulation plays an important role in pathophysiology and therapeutic mechanism across the major psychiatric disorders. “Inflammation theory” might not be the full answer for the big picture of mental disorders, but it might explain high occurrence of somatic symptoms and comorbidity o...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Abstract The 'monoamine hypothesis' is insufficient in approaching the aetiology of psychiatric disorders or in developing novel therapies. Accumulating evidence suggests that inflammatory regulation plays an important role in pathophysiology and therapeutic mechanism across the major psychiatric disorders. "Inflammation theory" might not be the full answer for the big picture of mental disorders, but it might explain high occurrence of somatic symptoms and comorbidity of physical illness in certain subtypes of the heterogeneous groups. Due to the complexity of clinical manifestations and bio-psycho-soci...
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
ConclusionOur panoramic meta-overview suggests that exercise can be an effective adjunctive treatment for improving symptoms across a broad range of mental disorders.
Source: Sports Medicine - Category: Sports Medicine Source Type: research
CONCLUSIONS: The current findings highlight the importance of addressing opioid use disorders and alcohol use disorders and depression together to mitigate the risk of suicidal behavior. PMID: 31522694 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
Conclusion: Natural recovery after TBI may include delayed onset of functional decline or early recovery, followed by progressive deterioration, and is negatively affected by medical comorbidities. Results contribute to the growing evidence that TBI is most appropriately treated as a chronic medical condition complicated by a variety of comorbid conditions.
Source: The Journal of Head Trauma Rehabilitation - Category: Neurology Tags: Original Articles Source Type: research
Conclusions and discussionOur study showed significant associations between migraine headache and psychiatric disorders, as well as with role functioning and disability. The findings of our study emphasise the need for screening for psychiatric comorbidity among those with migraine and the development of appropriate interventions for this group.
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research
According to USAToday, nearly 21 million Americans struggle with substance addictions. That’s more than the number of people who have all cancers combined, and can mean 1 in 7 people will eventually suffer from an addiction. With such an epidemic in place, it is important to understand how the process of healing from an addiction works. This means learning what types of luxury treatment programs are available and asking questions like, how long is a luxury treatment program? Typically, luxury treatment programs can last anywhere from 30-90 days, depending on many factors. What Determines How Long a Luxury Treatment ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Drug Rehab Information luxury luxury drug rehabilitation luxury heroin rehab rehab center rehabilitation for drug addiction residential residential rehab Source Type: blogs
Purpose of review Physical activity has established the efficacy in improving physical health, mental health and cognition in the general population. Recent research has examined its potential as a preventive measure and/or adjunctive treatment for various mental health conditions. This review summarizes the recent evidence for physical activity in the management of major mental illnesses. Recent findings Emerging evidence suggests that physical activity may confer protection against depression and anxiety/stress disorders. There is robust evidence that structured and supervised physical activity, including aerobic an...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: PSYCHIATRY, MEDICINE AND THE BEHAVIOURAL SCIENCES: Edited by Mohan Isaac and Igor Filipcic Source Type: research
CONCLUSION: Mental and behavioural disorders are an important problem in rural and remote communities, and acute presentations trigger a considerable number of RFDS retrievals. PMID: 31347169 [PubMed - as supplied by publisher]
Source: Med J Aust - Category: General Medicine Authors: Tags: Med J Aust Source Type: research
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