Progression of keratoconus resulting from hormone replacement therapy

Torres-Netto et  al. recently reported a case of keratoconus progression caused by treatment for infertility.1 We had a similar unusual case of progression of stable keratoconus when a female patient was started on hormone replacement therapy for menopausal symptoms. Oral hormone replacement therapy is a mode of t reatment for menopausal symptoms and usually has a combination of estrogen and progesterone supplements.2 The serum level of estrogen in a woman on hormone replacement therapy increases and affects the corneal thickness and stiffness, which can become more pronounced in an already weakened keratocon ic cornea.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Letter Source Type: research