Utilization Rates and Clinical Outcomes of Hepatitis C Positive Donor Hearts in The Contemporary Era

Hepatitis C virus(HCV) donors should be categorized as HCV-viremic[Antibody(Ab) –or+/Nucleic Acid testing(NAT)+] or HCV Ab+ nonviremic(Ab+/NAT-). Whereas recipients of hearts from HCV-viremic donors will develop viremia but can likely be cured of HCV shortly after transplant with direct-acting antivirals (DAAs), recipients of hearts from HCV Ab+ nonviremic donors are highly u nlikely to become viremic or require DAAs. Given this important difference in risk, we assessed the utilization trends and post heart-transplantation(HT) outcomes of HCV-naïve (Ab-/NAT-), HCV-viremic and HCV Ab+ nonviremic donor hearts.

Source: The Journal of Heart and Lung Transplantation - June 27, 2019 Category: Transplant Surgery Authors: Shivank Madan, Snehal R. Patel, Kusha Rahgozar, Omar Saeed, Sandhya Murthy, Sasa Vukelic, Daniel B. Sims, Jooyoung Julia Shin, Daniel J. Goldstein, Ulrich P. Jorde Tags: Original Clinical Science Source Type: research