ARHGAP21-deficiency impairs hepatic lipid metabolism and improves insulin signaling in lean and obese mice.

In conclusion, liver of ARHGAP21-haplodeficient mice are more insulin sensitive, associated with higher lipid synthesis and lower lipid export.
PMID: 31247150 [PubMed - as supplied by publisher]

Source: Canadian Journal of Physiology and Pharmacology - June 26, 2019 Category: Drugs & Pharmacology Authors: Zangerolamo L, Soares GM, Vettorazzi JF, Amaral MEC, Carneiro EM, Olalla Saad ST, Boschero AC, Barbosa-Sampaio HCL Tags: Can J Physiol Pharmacol Source Type: research