The Role of Older Age in Normocytic Anaemia in Type 2 Diabetes Mellitus.

The Role of Older Age in Normocytic Anaemia in Type 2 Diabetes Mellitus. Curr Aging Sci. 2019 Jun 27;: Authors: Wee YH, Anpalahan M Abstract BACKGROUND: Older age has a significant association with anaemia. However, this has not been adequately investigated in the context of specific comorbidities such as type 2 diabetes mellitus(T2DM). OBJECTIVES: To investigate the role of age in normocytic anaemia(NCA) and the adverse outcomes of NCA in T2DM. METHODS: Patients with NCA, either unexplained or related to chronic kidney disease(CKD), were recruited from a diabetic clinic over six months. Anaemia was defined as a haemoglobin(Hb)
Source: Current Aging Science - Category: Geriatrics Tags: Curr Aging Sci Source Type: research

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ConclusionsOur study provides fundamental insights on the molecular mechanisms underlying POMC neuron malprogramming in obesogenic contexts.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 16 February 2020Source: Canadian Journal of DiabetesAuthor(s): Tomoyuki Kawada
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
This article aims to classify the severity grading assessments for both insulin resistance (IR) syndrome and status of pancreatic beta (β) islet cells’ function using the homeostasis model assessment method (that is; homeostasis model assessment-insulin resistance [HOMA-IR] and homeostasis model assessment-pancreatic beta (β) islet cells’ function [HOMA-B] indices) with the focus of disseminating this information rapidly for clinical use by physicians in their patients with dysfunctional regulation of glucose metabolism. It will also assist clinicians to prevent and screen for these individuals who ar...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
In this study, the core-shell polydopamine-coated magnetic nanomaterials were synthesized with one-step approach and applied as magnetic solid phase extraction adsorbents combined with LC-MS/MS for quantification of the diabetes drug glimepiride in beagle dog plasma. The Fe3O4@PDA nanomaterials have strong magnetic response, good dispersibility in aqueous solution, and numerous binding sites for π–π interaction and hydrogen bonding with glimepiride. Based on these merits, glimepiride could be quickly extracted and separated from plasma within 10min. The established method has good linearity (1-2000ng•mL-1)...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
Authors: Augstburger E, Héron E, Abanou A, Habas C, Baudouin C, Labbe A Abstract Ischemic optic neuropathies are among the leading causes of severe visual acuity loss in people over 50 years of age. They constitute a set of various entities that are clinically, etiologically and therapeutically different. Anatomically, it is necessary to distinguish anterior and posterior forms. From an etiological point of view, the diagnosis of the arteritic form due to giant cell arteritis requires emergent management to prevent blindness and even death in the absence of prompt corticosteroid treatment. When this diagnosi...
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
Publication date: Available online 15 February 2020Source: Clinica Chimica ActaAuthor(s): Yao-Chang Liu, Jen-Pi Tsai, Li-Hsuan Wang, Ming-Che Lee, Bang-Gee HsuAbstractBackgroundFibroblast growth factor 23 (FGF-23) has a role in arterial stiffness (AS) apart from regulating mineral metabolism. We investigated the association between FGF-23 concentration and peripheral AS in renal transplantation (RT) recipients.MethodsThe fasting blood samples of RT recipients (n=66) were collected and analyzed.ResultsA total of 29 (43.9%) RT recipients were classified under the peripheral AS group. The RT recipients in this group had a hig...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Taxi driver with diabetes and hepatitis B is fifth fatality outside mainland ChinaA taxi driver has died from the coronavirus in Taiwan, marking the first such death on the island and the fifth fatality outside mainland China from an epidemic that has curbed travel and disrupted global supply chains.The health minister, Chen Shih-chung, said during a news conference on Sunday that the deceased was a 61-year-old man who had diabetes and hepatitis B. Taiwan has to date reported 20 confirmed cases.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Taiwan China Infectious diseases Medical research Science World news Asia Pacific Source Type: news
Evidence from studies and programs shows how crafting a meal can counter heart ailments, diabetes and other medical problems.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
We present the case of a 59-year-old patient with malabsorption syndrome which started with polyneuropathy. Capsule endoscopy and enteroscopy show villous denudation. Histological study confirms diaphragm disease of the small bowel. Diaphragm disease is a rare disease characterized by the presence of multiple thin diaphragms, such as septa, that narrow the intestinal lumen. The clinical features can be iron deficiency anemia, intestinal obstruction, change in bowel habits or acute abdomen secondary to perforation. It is usually generally with sustained use of high doses of non-steroidal anti-inflammatory drugs. The diagnos...
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
Authors: Fernández Conesa M, Milena Muñoz A, Valero González MÁ Abstract We read with interest the article by Guido Villa-Gómez, Manuel Alejandro Mahler and Dante Manazzoni "A new case of pseudoaneurysm of the right hepatic artery secondary to laparoscopic cholecystectomy". A 57-year-old cholecystectomized female was admitted due to abdominal pain with an analytical pattern of cholestasis and liver enzyme alterations, with cholangitis that progressed to septic shock of a biliary origin with gradual anemia and hypotension. PMID: 32054281 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
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