Characterization of a novel percutaneous closed chest swine model of ischemic mitral regurgitation guided by contrast echocardiography.

Characterization of a novel percutaneous closed chest swine model of ischemic mitral regurgitation guided by contrast echocardiography. EuroIntervention. 2019 Jun 25;: Authors: Hamza O, Kiss A, Kramer AM, Tillmann KE, Podesser BK Abstract INTRODUCTION: Alternative approaches for mitral valve repair are being constantly developed. Even though the safety of these devices has been extensively assessed in healthy animals before approval for first-in-man studies, often the efficacy of these new devices has been hardly challenged in vivoin the setting of MR. Therefore, reliable and reproducible preclinical animal models of MR are crucial to allow not only the safety assessment but also the efficacy evaluation of these novel approaches. PMID: 31235459 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research