A TRIM32-AMBRA1-ULK1 complex initiates the autophagy response in atrophic muscle cells.
In conclusion, we have identified a novel molecular mechanism by which autophagy is regulated in muscles, whose alteration is associated with the development of muscular dystrophy.
PMID: 31234693 [PubMed - as supplied by publisher]
Source: Autophagy - Category: Cytology Authors: Di Rienzo M, Piacentini M, Fimia GM Tags: Autophagy Source Type: research