Efficacy of azithromycin in a mouse pneumonia model against hospital-acquired methicillin-resistant Staphylococcus aureus.

In conclusion, contrary to the situation in vitro, AZM was effective against MRSA growth in vivo in our pneumonia model, substantially improving survival. The suppressive effect on MRSA growth at the initial stage of pneumonia could underlie the potential mechanism of AZM action against MRSA pneumonia. PMID: 31235625 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31235625?dopt=Abstract

Source: Antimicrobial Agents and Chemotherapy - June 23, 2019 Category: Microbiology Authors: Yamashita Y, Nagaoka K, Kimura H, Suzuki M, Konno S, Fukumoto T, Akizawa K, Kaku N, Morinaga Y, Yanagihara K Tags: Antimicrob Agents Chemother Source Type: research