Drug-induced gene expression profile changes in relation to intestinal toxicity: State-of-the-art and new approaches

The intestines are one of the organs that compose the lower gastrointestinal (GI) tract, being mainly responsible to turn food into nutrients and energy, expelling the waste as faeces. The intestines present a distinctive architecture that supports the important and complex functions of this organ and they are divided into small and large intestine. Each part presents a unique structure and metabolic activity [1], has a different composition of cells [2], expression of genes/proteins [3] and composition of the microbiome [4].
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Complications of Treatment Source Type: research