Sesquiterpene lactones and other secondary metabolites from Crepis commutata (Spreng.) Greuter – Asteraceae

Publication date: October 2019Source: Biochemical Systematics and Ecology, Volume 86Author(s): Ioanna Kotti, Christina Barda, Anastasia Karioti, Helen SkaltsaAbstractSesquiterpene lactones, especially guaianolides, are widespread in the genus Crepis L. We have undertaken the chemical investigation of Crepis commutata (Spreng.) Greuter, an edible plant in Crete. From the non-polar extract of the aerial flowering parts of C. commutata five sesquiterpene lactones: 8-epi-grosheimin (1), 8-epi-isoamberboin (2), 8-epi-isolipidiol (3), 3-acetyl-8-epi-isolipidiol (4), integrifolin 3-O-β-D-glucopyranoside (5), two flavonoids: luteolin (6), luteolin 7-O-β-D-glucuronide (7), and three phenolic acids: p-anisic acid (8), p-hydroxyphenylacetic acid (9) and E-caffeic acid (10) were isolated. The structures of the isolated compounds were elucidated by high-field NMR spectroscopy.Graphical abstract
Source: Biochemical Systematics and Ecology - Category: Biochemistry Source Type: research