Shortage of isosorbide mononitrate 10mg, 20mg and 40mg tablets

Source: Department of Health (DH) Area: News The Department of Health has issued a letter highlighting a current shortage of all normal release isosorbide mononitrate presentations (10, 20 and 40mg tablets) because of problems with the availability of raw materials.   The shortage of this medicine may last for several months and current information indicates that normal supply is unlikely to resume before the end of April 2013. However, the situation may change from week to week, as it is understood that some companies may obtain some stock before that time, while others are importing unlicensed isosorbide mononitrate for use on an individual patient basis.   In the absence of normal release isosorbide mononitrate tablets being available, clinicians are advised to consider substitution with a slow release mononitrate preparation (which are not affected by this supply problem). Limited data exist regarding switching from normal release to modified release tablets but initially a mg per mg substitution would ...
Source: NeLM - News - Category: Drugs & Pharmacology Source Type: news