Sleep apnea and the impact on cardiovascular risk in patients with Marfan syndrome
ConclusionsOur study shows a high prevalence of OSA and a high prevalence of overweight in MFS patients. We found some trends between OSA and cardiovascular features but we could not establish a solid association. Our study, however might be underpowered, and a multicenter collaborative study could be very useful to answer some important open questions.
Publication date: Available online 15 November 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Amanda D'Espessailles, Natalia Santillana, Sofía Sanhueza, Cecilia Fuentes, Mariana CifuentesAbstractExcess adipose tissue (AT) associates with inflammation and obesity-related diseases. We studied whether calcium-sensing receptor (CaSR)-mediated NLRP3 inflammasome activation in THP-1 macrophages elevates inflammation in LS14 preadipocytes, modeling deleterious AT cell crosstalk. THP-1 macrophages exposed to Cinacalcet (CaSR activator, 2 μM, 4 h) showed elevated proinflammatory marker and NLRP3 inflammaso...
ConclusionAccording to the results, whey supplementation significantly reduced the SBP, DBP, HDL, waist circumference, TG and FBS in intervention groups in comparing to control groups.
ConclusionHigh prevalences of underweight and overweight/obesity were identified in ASEAN countries and several correlates were identified which can help to tailor interventions.
ConclusionThe Wallace rule of nines is a quick and acceptable method for estimating the total burn surface area percentage in men of all BMI ranges. However, for women, a more accurate method of burn area estimation is required as proposed by our BMI adjusted charts.
ConclusionThis is the first report on the synthesis of two novel ginsenosides, namely glucosyl-ginsenoside Rh2 and diglucosyl-ginsenoside Rh2 from Rh2 by utilizing recombinant glycosyltransferase isolated from L. rhamnosus. Moreover, diglucosyl-ginsenoside Rh2 might be a new candidate for treatment of inflammation, obesity and skin whiting, and especially for anticancer.Graphical abstract
Atrial fibrillation (AF) is the most common arrhythmia and poses a substantial economic burden due to associated thromboembolic complications. Screening for AF may theoretically be effective, but there is no consensus regarding the optimal screening method because the available tools are either invasive or not cost-effective. Recently, smartwatch industry has received a surge of interest for this purpose by introducing technologies such as photoplethysmography, artificial intelligence, and actual electrodes taking an electrocardiogram to measure and analyze heart rate and rhythm with relatively acceptable accuracy. Combine...
Conclusions: Although additional research needs to be conducted, either an abnormal stress test or abnormal ABI suggested an increase of MCE at 1 year with abnormal stress test and ABI demonstrating the highest risk. The addition of ABI to patients undergoing stress testing may enhance risk stratification in patients who present with chest pain.
ConclusionsIn people with obesity, exposure to weight-stigmatising media may contribute to increased BMI over time. Larger trials with longer follow-up are needed to confirm these findings.
Insomnia can be a disruptive condition that affects your entire life. When you aren’t able to sleep at night, it can negatively impact issues in almost every area of your life and well-being. If you are taking sleeping pills or are thinking about starting to take sleeping pills, make sure you know as much as possible about all the sleeping pill side effects. What Are Sleeping Pills and How Do They Work? Sleeping pills are used to treat insomnia. According to the National Sleep Foundation, insomnia is described as difficulty falling asleep or staying asleep, even when a person has the chance to do so. People with ins...
Abstract Objective: Primary headache and obesity are highly prevalent disorders in the general population. Although many studies have reported an association between the two, there is still no overall comprehension about this relationship. To gain a more accurate understanding in this regard, we analyzed data from a 2011 cross-sectional study in Chongqing, China. Methods: Patients with a chief complaint of headache were administered a headache questionnaire and diagnosed by neurology doctors in accordance with the International Classification of Headache Disorders 2nd Edition (ICHD-II) criteria. Patients aged