Combination Therapy for Rosacea Shows Improved Response Rates

WEDNESDAY, June 26, 2019 -- Combining ivermectin cream (IVM) and doxycycline modified-release capsules (DMR) can improve response rates for patients with severe rosacea, according to a study recently published in the Journal of the American Academy...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
Conclusion: The results of this study suggest that the increased expression of mast cells may be a sign of chronic, later stage of granulomatous rosacea compared to the erythematotelangiectatic rosacea. The increased expression of toll-like receptor 2 suggests that cathelicidin-induced neuroimmune pathogenesis also contributes to the pathophysiology of granulomatous rosacea.
Source: Indian Journal of Dermatology - Category: Dermatology Authors: Source Type: research
Conclusion: There has been a definite change in the lifestyle due to the current Covid-19 pandemic. People are compulsorily using face masks to avoid the spread of Covid-19 infection. This change in behavior has brought out a surge of rosacea like lesions on the covered area of face. Partly, it can be explained by change in innate immunity due to excessive sweating and change in microenvironment of skin.
Source: Indian Journal of Dermatology - Category: Dermatology Authors: Source Type: research
Condition:   Rosacea, Topical Herbal Medicine Intervention:   Drug: dian dao san Sponsor:   Chang Gung Memorial Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractRosacea is a chronic inflammatory skin condition that is associated with multiple systemic comorbidities, with the strongest evidence linking rosacea to hypertension, dyslipidemia, inflammatory bowel disease, and anxiety and depression. To assess dermatologists ’ awareness of and screening practices for rosacea comorbidities, we developed a survey that was distributed to attendings and residents across four academic dermatology departments in Massachusetts. A total of 73 dermatologists with varying experience participated in the study. Findings demonstra ted significant knowledge and practice gaps among acade...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
Conclusion: Pruritus, pain, or other sensory symptoms were found to be common not only in classic pruritic skin diseases but also in acne, rosacea, or warts. The association of pruritus and pain dramatically increased psychological suffering. These symptoms must be systematically searched for in patients, especially since new therapeutic possibilities are emerging for the symptomatic treatment of pruritus.Dermatology
Source: Dermatology - Category: Dermatology Source Type: research
Australas J Dermatol. 2021 Sep 7. doi: 10.1111/ajd.13711. Online ahead of print.NO ABSTRACTPMID:34490894 | DOI:10.1111/ajd.13711
Source: The Australasian Journal of Dermatology - Category: Dermatology Authors: Source Type: research
Ocul Surf. 2021 Sep 1;22:224-229. doi: 10.1016/j.jtos.2021.08.017. Online ahead of print.ABSTRACTRosacea is a common chronic skin disease affecting mostly people aged 40 and above, with currently no cure. When it affects the eyelids and periocular skin, it leads to dry eye and potentially corneal damage. Research performed over the last decade shed light into the potential mechanisms leading to skin hypersensitivity and provided promising avenues for development of novel, rational therapeutics aimed at reducing the skin inflammatory state. In this review, we discuss the current knowledge on the mechanisms of rosacea in gen...
Source: The Ocular Surface - Category: Opthalmology Authors: Source Type: research
ConclusionNasal rosacea has relatively specific clinical features and independent risk factors, suggesting that it may be a special type of rosacea.
Source: Dermatology and Therapy - Category: Dermatology Source Type: research
AbstractRosacea is a chronic inflammatory skin disease characterized by centrofacial erythema, papules, pustules, and telangiectasias. The onset of rosacea typically occurs after 30  years of age. It is estimated that approximately 2–5% of adults worldwide are affected. While the exact etiology of rosacea remains unknown, its pathogenesis is thought to be multifactorial with both environmental and genetic factors implicated. Ultraviolet radiation, heat, steam, ingested agent s, including spicy foods and alcohol, host vasculature, dermal matrix degeneration, genetic susceptibility, and microbial organisms, includ...
Source: Dermatology and Therapy - Category: Dermatology Source Type: research
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