No Early Cancer Risk With Donor Lungs From Heavy Smokers

LOS ANGELES (IMNG) - Use of lungs from donors who smoked heavily does not worsen lung transplantation outcomes including risk for lung cancer death, at least in the medium term.At a median follow-up of...
Source: OncologySTAT Latest News - Category: Cancer & Oncology Source Type: news

Related Links:

Development of primary lung cancer in donor lung post-lung transplantation is very rare, with few described cases. The safety of stereotactic ablative radiotherapy (SABR) for early-stage lung cancer arising fr...
Source: Radiation Oncology - Category: Cancer & Oncology Authors: Tags: Case report Source Type: research
A 39-year-old non-smoker woman was admitted in the thoracic oncology unit of the Montpellier Academic Hospital in June 2017 for investigation of multiple lung consolidations, fever, and respiratory failure. She was followed-up since infancy for a cystic fibrosis with cystic fibrosis transmembrane conductance regulator (CFTR) mutation ( ΔF508-CFTR). Two years ago, a lung allograft was decided, owing to rapid onset of respiratory function impairment, and she received a bi-pulmonary transplant. According to the donor database, the lung transplant was removed from a 57-year-old woman with a 30 pack-year smoking history.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: In our setting, excluding NMSC, the incidence is 8.8 times greater than estimations for the general population, with a high rate of lung cancer, so we should implement preventive and diagnostic strategies. PMID: 30017062 [PubMed - as supplied by publisher]
Source: Cirugia eEspanola - Category: Surgery Authors: Tags: Cir Esp Source Type: research
CONCLUSIONS: To date, data on OS, quality of life, PFS, response rate, or short- and long-term AEs are available from small uncontrolled trials only. The three trials included heavily pretreated participants, which had previously undergone regimens of BV or ASCT. For these participants, median OS was not reached after follow-up times of at least 16 months (more than 50% of participants with a limited life expectancy were alive at this timepoint). Only one cohort out of three only reported quality of life, with limited follow-up data so that meaningful conclusions were not possible. Serious adverse events occurred rarely. C...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
ConclusionsLTX and liver resections due to CD/CS are rare and associated with an acceptable post-operative morbidity and low mortality. Surgical treatment should be performed as early as possible to avoid recurrent episodes of cholangitis or carcinogenesis.
Source: Journal of Visceral Surgery - Category: Surgery Source Type: research
Publication date: 2018Source: Respiratory Medicine Case Reports, Volume 25Author(s): Pradnya D. Patil, Samir Sultan, M. Frances Hahn, Sreeja Biswas Roy, Mitchell D. Ross, Hesham Abdelrazek, Ross M. Bremner, Nitika Thawani, Rajat Walia, Tanmay S. PanchabhaiAbstractPatients under consideration for lung transplantation as treatment for end-stage lung diseases such as idiopathic pulmonary fibrosis (IPF) often have risk factors such as a history of smoking or concomitant emphysema, both of which can predispose the patient to lung cancer. In fact, IPF itself increases the risk of lung cancer development by 6.8% to 20%. Solid org...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Publication date: July 2018Source: Journal of Integrative Medicine, Volume 16, Issue 4Author(s): Bin Luo, Zu-jun Que, Zhi-yi Zhou, Qing Wang, Chang-sheng Dong, Yi Jiang, Bing Hu, Hui Shi, Yu Jin, Jian-wen Liu, He-gen Li, Lin Wang, Jian-hui TianAbstractObjectiveEscape from the body’s immune response is a basic characteristic of lung cancer, and indoleamine-2,3-dioxygenase (IDO) plays a key role in mediating immune escape of non-small-cell lung cancer, which leads to recurrence and metastasis. Feiji Recipe, a compound Chinese herbal medicine, has the effect of stabilizing lesions and prolonging survival in patients wit...
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
ConclusionsLTX and liver resections due to CD/CS are rare and associated with an acceptable post-operative morbidity and low mortality. Surgical treatment should be performed as early as possible to avoid recurrent episodes of cholangitis or carcinogenesis.
Source: Journal of Visceral Surgery - Category: Surgery Source Type: research
Publication date: 2018Source: Respiratory Medicine Case Reports, Volume 25Author(s): Pradnya D. Patil, Samir Sultan, M. Frances Hahn, Sreeja Biswas Roy, Mitchell D. Ross, Hesham Abdelrazek, Ross M. Bremner, Nitika Thawani, Rajat Walia, Tanmay S. PanchabhaiAbstractPatients under consideration for lung transplantation as treatment for end-stage lung diseases such as idiopathic pulmonary fibrosis (IPF) often have risk factors such as a history of smoking or concomitant emphysema, both of which can predispose the patient to lung cancer. In fact, IPF itself increases the risk of lung cancer development by 6.8% to 20%. Solid org...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Publication date: July 2018Source: Journal of Integrative Medicine, Volume 16, Issue 4Author(s): Bin Luo, Zu-jun Que, Zhi-yi Zhou, Qing Wang, Chang-sheng Dong, Yi Jiang, Bing Hu, Hui Shi, Yu Jin, Jian-wen Liu, He-gen Li, Lin Wang, Jian-hui TianAbstractObjectiveEscape from the body’s immune response is a basic characteristic of lung cancer, and indoleamine-2,3-dioxygenase (IDO) plays a key role in mediating immune escape of non-small-cell lung cancer, which leads to recurrence and metastasis. Feiji Recipe, a compound Chinese herbal medicine, has the effect of stabilizing lesions and prolonging survival in patients wit...
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
More News: Cancer | Cancer & Oncology | Lung Cancer | Lung Transplant | Smokers | Transplants