Gut Pathogens celebrates its 10th anniversary

Gut Pathogens was founded in 2009 as a journal focusing on enteric infections and aimed at an audience in the Global South and middle income countries. The focus of the first articles remained directed at virulence, epidemiology and genomics of classical pathogens. However, soon after the developments in the field of probiotics turned the journal into a preferred venue for research on this topic. Furthermore, parallel developments in genomics of bacteria resulted in an increase of short articles documenting bacterial genomics, and this led us to create a new short article type called Genome Announcements. Soon after, the single draft genomes became too pedestrian and the announcements were then made into a different article type, called Genome Reports, which entailed somewhat elaborate descriptions involving comparative genomics as well. Then came the time of microbiota analyses and related association studies. Another important area that has emerged of relevance to the journal is antimicrobial resistance. All these areas of works in medical microbiology have made Gut Pathogens a sought-after venue for first class research not only emanating from the Global South and lower-middle income countries, but also from the high income world. Research highlights In the past years, Gut Pathogens published several studies that attracted remarkable visibility from the research community and the wider audience. Among the others, a review published in 2011 provided insights on the ability ...
Source: BioMed Central Blog - Category: General Medicine Authors: Tags: Biology Developing World Health Medicine bacterial genomics enteric infections gastroenterology gut gut pathogens gut-brain axis microbiome Source Type: blogs

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The objective of this study was to measure gene expression of various preadipocyte, proliferation, metabolic, and apoptotic markers in the stromal-vascular fraction and adipocytes from LWS and HWS adipose tissue. Although preadipocyte and proliferation markers were more highly expressed in the stromal-vascular fraction of LWS than HWS chicks, greater expression of granzyme-A and the presence of more annexin V-positive cells suggests that apoptosis may limit the adipogenic potential of adipocyte precursor cells and represent a novel mechanism that regulates the expansion of adipose tissue. Results provide insights on cellul...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - Category: Biochemistry Source Type: research
Authors: Öztürk H, Özen B, Çatlı G, Dündar B Abstract Background: Macular damage may be observed in obesity and metabolic syndrome (MetS) that lead to chronic subclinical inflammation and affect almost all organ systems. Objectives: The purpose of this study was to investigate the relations of macular variability with anthropometric measurements, metabolic parameters, and inflammatory markers in children and adolescents with MetS. Methods: Two hundred twenty-eyes of 62 obese and 48 healthy children and adolescents were included in the study. Bilateral macular retinal thickness (M...
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Conclusion: Obesity prevalence of our T1D cohort is similar to healthy population in the same ages. Prevalence of MetS is higher in children and adolescents with T1D compared to the obese population in our country. Our study suggests that IDF criteria are more suitable for the diagnosis of MetS in children and adolescents with T1D. PMID: 31434460 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Publication date: 15 January 2020Source: Journal of Hazardous Materials, Volume 382Author(s): Thomas F. Ducey, Lisa M. Durso, Abasiofiok M. Ibekwe, Robert S. Dungan, Charlene R. Jackson, Jonathan G. Frye, B. Lana Castleberry, Diana M.C. Rashash, Michael J. Rothrock, Debbie Boykin, Terence R. Whitehead, Zeanmarj Ramos, Morgan McManus, Kimberly L. CookAbstractThere are limited numbers of Escherichia coli isolate panels that represent United States food animal production. The majority of existing Escherichia coli isolate panels are typically designed: (i) to optimize genetic and/or phenotypic diversity; or (ii) focus on human...
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
A Case of Bacteriologically Determined De NovoTuberculosis during Tumor Necrosis Factor-α Inhibitor Therapy. Intern Med. 2019 Aug 21;: Authors: Takahashi G, Kobayashi H, Saito Y, Ohsawa S, Suzuki K, Ishihara S, Hisada T Abstract A 58-year-old man with Crohn's disease received adalimumab for 13 months after screening results for tuberculosis were found to be negative. He was diagnosed with de novo mediastinal lymph-node tuberculosis, which was proved to be bacteriologically identical to that of an individual with smear positive lung tuberculosis by a variable number of tandem repeat analyses. Afte...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
AbstractAfrican Americans and ethnic minorities experience racial discrimination in a variety of settings. Racial discrimination is a potent stressor that has been linked to psychosocial stress and poor physical health. To cope with discriminatory experiences and daily life event stressors, African Americans frequently use the concept of John Henryism (a high effort coping strategy with prolonged exposure to stress). This cross-sectional analysis explored the relationship between racism/discrimination, John Henryism, and health problems in a predominately African American sample. Data were collected through health care scr...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
Neck and back pain caused by intervertebral disc (IVD) degeneration is a frequent cause of referral to spine surgeons. This is a multifactorial disease process caused by aging, injury, obesity, and mechanical stress. Recently, an association between IVD degeneration and diabetes has been identified, but the mechanisms underlying this relationship are unclear. Furthermore, the effects of insulin levels on cytokines known to be elevated in diabetics have not previously been delineated. Uncontrolled diabetes results in chronic systemic inflammation with increased circulating levels of IL-6 and IL-18.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Bariatric surgery for morbid obesity helps to address common comorbidity burdens, including decreasing rates of myocardial infarction and stroke. The increased mechanical stresses on the spine caused by morbid obesity predispose patients to various spinal pathologies and are concerning for spinal surgeons, with previous studies suggesting poorer outcomes than the general population. The effects of bariatric surgery on diminishing spinal complaints or symptoms have yet to be elucidated in the literature.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Obese patients, particularly those with a body mass index (BMI) ≥35 kg/m2, pose a major challenge for a spine surgeon. Though obesity has previously been shown to be linked with adverse outcomes following elective spine surgical procedures, the impact of prior bariatric surgery on altering postoperative outcomes following elective anterior cervical discectomy and fusions (ACDFs) has not been explored.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Obesity has been shown to be associated with higher rates of complications following lumbar spine surgery. However, the evidence regarding the impact of increasing body mass index (BMI) on postoperative outcomes following posterior cervical fusions remains limited.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
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