Reply to: “Assessment and treatment of ischemia reperfusion injury: The real challenge of uncontrolled donation after circulatory death”

We welcome the opportunity to comment on this letter on our editorial.1 We also wish to acknowledge the efforts made by Dr Lazzeri and her colleagues in introducing successful controlled and uncontrolled donation after circulatory death (cDCD and uDCD) programs, despite the local challenges highlighted by the author. We agree that interventions to minimise the damage caused by the inevitable warm ischaemic time and subsequent reperfusion injury are essential in this form of deceased donation, and that in-situ or ex-situ perfusion techniques are showing promise in improving organ utilisation and transplant outcomes of organs retrieved from both cDCD or uDCD donors.
Source: Resuscitation - Category: Emergency Medicine Authors: Tags: Letter to the Editor Source Type: research