Toward improving prognosis prediction in patients undergoing small lung adenocarcinoma resection: Radiological and pathological assessment of diversity and intratumor heterogeneity

Lung cancer is the leading cause of cancer-related death and third most common cancer in Japan [1]. Lung adenocarcinoma is the most common histological type of lung cancer [2]. Adenocarcinomas shows diversity across both the radiologic and pathologic spectrums. Additionally, the internal structure of adenocarcinomas is heterogeneous. Radiologically, adenocarcinoma often consists of various ratios of ground-glass opacity (GGO) and solid components. GGO is defined as an opacity that does not obscure the underlying structures or vasculature on high-resolution computed tomography (CT) [3], whereas solid components are defined by an increase in attenuation that obscures the underlying vascular markings.
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research