[Erythroderma revealing IPEX syndrome].
CONCLUSION: The early onset of severe cutaneous manifestations with persistent lesions and poor response to topical steroids should lead to an early skin biopsy. If histopathological changes show a cytotoxic lymphocytic infiltrate with keratinocyte necrosis, a diagnosis of primary immunodeficiency must be considered enabling rapid intitation of specific management.
PMID: 31230776 [PubMed - as supplied by publisher]
Source: Annales de Dermatologie et de Cenereologie - Category: Dermatology Authors: Bachelerie M, Merlin E, Beltzung F, Franck F, Joubert J, Hall T, Fraitag S, D'Incan M Tags: Ann Dermatol Venereol Source Type: research