Letter to the Author, concerning the publication: Amyloid pathology fingerprint differentiates post-traumatic stress disorder and traumatic brain injury. Mohamed AZ, et al. Neuroimaging Clinical 2018 Jun 5;19:716–726

Publication date: Available online 24 June 2019Source: NeuroImage: ClinicalAuthor(s): Susan Landau, Danielle Harvey, Michael W. WeinerAbstractOver the past six months, we have been in discussion with you and the authors of a recent publication in NeuroImage: Clinical (Amyloid pathology fingerprint differentiates posttraumatic stress disorder and traumatic brain injury. Mohamed AZ, et al. Neuroimaging Clinical 2018 Jun 5;19:716–726). We raised a variety of methodological concerns with Mohamed and colleagues and discussion about these concerns led to their preparation of a corrigendum to be published in NeuroImage: Clinical.We appreciate that the authors were responsive to our concerns and made a number of changes as noted in the corrigendum. Ultimately, however, the corrigendum does not address the primary conclusions of the study, which we were unable to replicate. We are troubled by the publication of results that cannot be replicated using identical methods and participant data.This is a letter to the authors to address these concerns.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research

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Publication date: Available online 13 July 2019Source: Brain, Behavior, and ImmunityAuthor(s): Seyma Katrinli, Adriana Lori, Varun Kilaru, Sierra Carter, Abigail Powers, Charles F. Gillespie, Aliza P. Wingo, Vasiliki Michopoulos, Tanja Jovanovic, Kerry J. Ressler, Alicia K. SmithAbstractBackgroundImmune dysregulation has been widely observed in those with posttraumatic stress disorder (PTSD). An individual’s immune response is shaped, in part, by the highly polymorphic Human Leukocyte Antigen (HLA) locus that is associated with major psychiatric disorders such as schizophrenia, major depression and bipolar disorder. ...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Contributors : Ren Xiaoqing ; Hu BoqiangSeries Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencing ; OtherOrganism : Homo sapiensChromobox homolog 4 (CBX4), a component of polycomb repressive complexes 1 (PRC1), plays important roles in the maintenance of cell identity and organism development through epigenetic silencing. However, it remains unclear whether CBX4 regulates the homeostasis of human stem cells. Here, we demonstrate that CBX4 counteracts human mesenchymal stem cell (hMSC) aging via the maintenance of nucleolar homeostasis. CBX4 protein d...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing Other Homo sapiens Source Type: research
ConclusionsEmotion regulation strategies could mediate the relationship between dispositional mindfulness and posttraumatic outcomes in different ways. These findings highlight the beneficial effects of dispositional mindfulness on firefighters' mental health.
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
AbstractDespite the occurrence of several earthquakes, only a few studies were conducted in Italy on the psychological impact in children and adolescents, with data mostly collected within one year after the disaster. This cross-sectional study aimed at exploring the prevalence of both post-traumatic stress disorder (PTSD) and emotional/behavioral difficulties, as well as at identifying their main predictors, among youths 2 years after the earthquake that hit Northern Italy in 2012. 682 children and adolescents (9 –14 years) living in two districts (earthquake zone vs control zone) were administered an exposure ...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
MATTHEW WRIGHT had presented The Wright Stuff for a whopping 18 years - but after leaving last year, Wright explained how the years of waking up so early impacted his health negatively.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
from SharpBrains We hope you enjoy this slidedeck supporting two sessions held during the 2019 SharpBrains Virtual Summit: The Future of Brain Health (March 7–9th).  Full recordings are available for purchase here. 8–8.45am. Rethinking and Retooling Brain Health and Mental Health   Dr. Tom Insel, Co-founder and President of Mindstrong Health and former Director of the National Institute of Mental Health (NIMH) 9–10.30am. How to detect problems early: Examples in Alzheimer’s Disease, Parkinson’s, anxiety and PTSD Dr. Srijan Sen, Professor of Depressi...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology brain health digital mental health Dolby Family Ventures Merck Ventures Mindstrong Health NeuraMetrix Rethinking retooling University-of-Michigan Source Type: blogs
There is a dearth of information about the association of victim-related and assailant-related characteristics and posttraumatic stress disorder (PTSD) among sexually assaulted women. Recently, Statistics Canada included items measuring the possible presen...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
(1) Background: Work-related stress is a major contributor to human error. One significant workplace stressor is job insecurity, which has been linked to an increased likelihood of experiencing burnout. This, in turn, might affect human error, specifically...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Traumatic brain injury (TBI) is one of the main causes of mortality and morbidity worldwide with no suitable treatment. The present study was designed to review the present literature about the protective effects of curcumin and the underlying mechanism ag...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
In the present study, the relation between bedtime procrastination and death anxiety, and also the moderator roles of gender and purpose in life were investigated. Data were collected from 245 participants through an online survey. The results revealed tha...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
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