Targeting the differentiation of gastric cancer cells (KATO ‑III) downregulates epithelial‑mesenchymal and cancer stem cell markers.

In conclusion, the induction of the differentiation of cancer stem cells into non‑proliferating cells offers the possibility for novel drug design to overcome the issues associated with metastasis, drug resistance and systemic toxicity with improved therapeutic efficacy. PMID: 31233198 [PubMed - as supplied by publisher]
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research