Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

Ethanol withdrawal (EtOHW) anxiety is a crucial risk factor for alcoholic relapse. The neuropeptide nociceptin/orphanin FQ (N/OFQ) acts upon its receptor (NOP) to antagonize corticotropin-releasing factor (CRF...

Source: BMC Complementary and Alternative Medicine - June 24, 2019 Category: Complementary Medicine Authors: Li Bo Li, Young Woo Kim, Yu Hua Wang, Li Bai, Xiao Dong Zhu, Zheng Lin Zhao, Chul Won Lee, Yu Jiao, Tong Wu, Zhen Zhen Cai, Sang Chan Kim, Won G. An, Chae Ha Yang, Guang Cheng Cui and Rong Jie Zhao Tags: Research article Source Type: research