Permanent and Transient Electrophysiological Effects During Cardiac Cryoablation Documented by Optical Activation Mapping and Thermal Imaging

Conclusion: Transient EP changes were observed surrounding the permanent cryo lesion (<-5 °C), including conduction block (-5 to 17 °C), and reduced conduction velocity (>17 °C). Significance: The observed changes explain effects observed during clinical cryoablation, including transient increases in effective ref- actory period, transient conduction block, and transient slowing of conduction. The presented quantitative data on temperature dependence of EP effects may enable the prediction of the effects of clinical cryoablation devices.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research