Parallel evolution leading to impaired biofilm formation in invasive < i > Salmonella < /i > strains

We present new evidence in support of parallel evolution between lineages of nontyphoidalSalmonella associated with invasive disease in Africa and the archetypal host-restricted invasive serovar;S. Typhi. We hypothesize that the African invasive isolates are becoming human-adapted and ‘niche specialized’ with less reliance on environmental survival, as compared to gastroenteritis-causing isolates.

Source: PLoS Genetics - June 23, 2019 Category: Genetics & Stem Cells Authors: Keith D. MacKenzie Source Type: research