Female sex hormones and risk of incident abdominal aortic aneurysm in Norwegian women

The delayed development of abdominal aortic aneurysm (AAA) in women compared with men might be secondary to a protective effect from endogenous estrogens. The role of postmenopausal hormone therapy remains unclear. The aim of the present study was to evaluate the effect of female sex hormones compared with other risk factors associated with AAA through a long-term study of a large female cohort.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research

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CONCLUSION: TF-TAVI can be performed successfully in patients with aortic disease or previous endovascular aortoiliac intervention. Simultaneous and sequential (T)EVAR is feasible. PMID: 31416046 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
Abdominal aortic aneurysm (AAA) is a common disease; however, its exact pathogenesis remains unknown, and no specific medical therapies are available. Interleukin (IL)-18 plays a crucial role in atherosclerotic plaque destabilization and is a strong predictor of cardiovascular death. Here, we investigated the role of IL-18 in AAA pathogenesis using an experimental mouse model.
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
Different abdominal aortic aneurysm (AAA) mouse models have been used over the last two decades. Here, the main AAA models will be highlighted, and what has been learned from them will be discussed.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Edutorial Source Type: research
CONCLUSIONS: In the rural context, POCUS AAA is a reliable 'rule out' test for ruptured abdominal aortic aneurysm and FAST scan has a role as a 'rule in' test for solid organ injury. These findings are consistent with larger studies in the emergency medicine literature. PMID: 31401838 [PubMed - in process]
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
Conclusions: Although super-utilizers accounted for only 5.3% of patients, these patients accounted for 39.6% of total Medicare expenditures in the year before surgery. Among a subset of super-utilizers, surgical intervention was associated with a reduction in annual Medicare expenditure in the year after surgery.
Source: Annals of Surgery - Category: Surgery Tags: PAPERS OF THE 139TH ASA ANNUAL MEETING Source Type: research
Abstract BACKGROUND: Data are conflicting on sex differences in ruptured abdominal aortic aneurysm (rAAA) repair rates and outcomes have rarely been addressed. The aim of this study was to investigate differences in the management and outcome of rAAA in men and women, and to describe time trends over a 15-year interval. METHODS: Data on patients with rAAA were extracted from the Swedish National Patient Registry and the Cause of Death Registry for the interval 2001-2015. The study included patients with rAAA whether or not they were admitted to any hospital in Sweden. A propensity score-matched model was used...
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
Endologix has received investigational device exemption (IDE) approval from FDA for a new pivotal study to evaluate the safety and effectiveness of the Nellix Chimney Endovascular Aneurysm Sealing System for the endovascular treatment of complex abdominal aortic aneurysms (AAA). The system is an endovascular abdominal aortic aneurysm therapy designed to combine the Nellix 3.5 endograft with parallel visceral stents to enable treatment of patients with juxta-renal, para-renal, and suprarenal AAA. The application of endovascular aneurysm sealing for patients with complex aneurysms will offer innovativ...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Regulatory and Compliance Source Type: news
This study reports outcomes up to 5  years for Nellix (Endologix, Irvine, Calif) EVAS.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
Juxtarenal Aortic Aneurysm: Are We Ready for a Randomised Trial on Open versus Endovascular Repair? Commentary on "Durability of Open Repair of Juxtarenal Abdominal Aortic Aneurysms. A Multicentre Retrospective Study in Five French Academic Centres". Eur J Vasc Endovasc Surg. 2019 Aug 09;: Authors: Lepidi S, Squizzato F PMID: 31405728 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - Category: Surgery Authors: Tags: Eur J Vasc Endovasc Surg Source Type: research
In the last two decades, advances in endovascular aneurysm repair (EVAR) technology have led to the introduction of fenestrated (fEVAR) and branched (bEVAR) stent grafts for the treatment of juxta- and suprarenal abdominal aortic aneurysms (JRAAAs and SRAAAs), extending the proximal sealing zone from the infrarenal to the suprarenal aorta and expanding the EVAR indications to complex abdominal aortic aneurysms (AAAs).
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Invited Commentary Source Type: research
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