Opioid use after ankle fracture surgery: current trends in the United States

Conclusions: The percentage of patients utilizing opioid prescriptions after ankle fracture surgery is much lower than expected, suggesting that routine prescriptions given after ankle fracture surgery and other smaller orthopaedic procedures are not likely to be contributing to the epidemic.
Source: Current Orthopaedic Practice - Category: Orthopaedics Tags: Original Research Source Type: research

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Publication date: Available online 20 July 2019Source: Antiviral ResearchAuthor(s): Nicholas Klaiber, Michael A. McVoy, Wei ZhaoAbstractEnterovirus D68 (EV-D68) represents an emerging pathogen which has demonstrated a capacity for causing epidemic illness in pediatric and immunocompromised patients. With no effective antiviral treatment available, therapeutic interventions are currently limited to supportive care. Utilizing available genomic sequences from the 2014 B3 Epidemic EV-D68 clade and the 1962 Fermon EV-D68 strains, we performed in silico comparative genomic analysis, identifying several islands of phylogenetic co...
Source: Antiviral Therapy - Category: Virology Source Type: research
From the European Congress of Virology in Rotterdam, Vincent and local co-host Ben Berkhout speak with Ron Fouchier, Rosina Girones, and Marie-Paule Kieny about their careers and their work on influenza virus, environmental virology, and developing an Ebola virus vaccine during an epidemic. Hosts: Vincent Racanielloand Ben Berkhout Guests: Ron Fouchier, Rosina Girones, and Marie-Paule Kieny Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ECV2019 Drift of human H2N2 viruses (J Viral) Viruses in urban sewage (Sci Tot Environ) Ebola ...
Source: This Week in Virology - MP3 Edition - Category: Virology Authors: Source Type: podcasts
Publication date: Available online 19 July 2019Source: Journal of Theoretical BiologyAuthor(s): Soyoung Kim, Eunok JungAbstractWe developed a mathematical model of the 2009 A/H1N1 influenza epidemic in the Republic of Korea by considering five age groups and suggested the best way to prioritize an age-dependent vaccination strategy for mitigating the epidemic. An age-structured SEIAR influenza model was constructed based on the laboratory confirmed data obtained from the Korea Centers for Disease Control and Prevention (KCDC). The estimated transmission matrix captured one of the main characteristics of the 2009 A/H1N1 inf...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
We describe the implementation of index testing and PNS under the Zimbabwe HIV Care and Treatment (ZHCT) project and the resulting uptake, HIV positivity rate and links to HIV treatment. METHODS: The ZHCT project has been implemented since March 2016, covering a total of 12 districts in three provinces. To assess the project's performance on index testing, we extracted data on HIV testing from the district health information system (DHIS 2) from March 2016 to May 2018, validated it using service registers and calculated monthly HIV positivity rates using Microsoft Excel. Data were disaggregated by district, province, s...
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
CONCLUSIONS: Including aPN as part of community-led HTS for key populations and their partners is feasible and effective, particularly for reaching first-time testers and undiagnosed HIV clients. Scale-up of aPN within community-led HTS for key populations is essential for achieving the United Nations 90-90-90 targets in Vietnam. PMID: 31321903 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
CONCLUSIONS: Steroid receptor coactivators are critical regulators of human metabolism with pleiotropic and tissue-specific actions. We believe that our study will contribute to the better understanding of the complex multi-tissue interactions that are disrupted in obesity and can therefore lead in numerous cardiometabolic diseases. Further on, present findings suggest that SRC-3/AIB-1 could constitute possible future drug targets. PMID: 31322077 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Publication date: Available online 19 July 2019Source: The Lancet HIVAuthor(s): Stefan Baral, Amrita Rao, Patrick Sullivan, Nancy Phaswana-Mafuya, Daouda Diouf, Greg Millett, Helgar Musyoki, Elvin Geng, Sharmistha MishraSummaryIn 2019, the HIV pandemic is growing and soon over 40 million people will be living with HIV. Effective population-based approaches to decrease HIV incidence are as relevant as ever given modest reductions observed over the past decade. Treatment as prevention is often heralded as the path to improve HIV outcomes and to reduce HIV incidence. Although treatment of an individual does eliminate onward t...
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
Cities and counties are suing major drugstore chains and Walmart, contending they distributed billions of painkillers that devastated communities.
Source: NYT - Category: American Health Authors: Tags: Opioids and Opiates Drugstores Suits and Litigation (Civil) Drug Enforcement Administration Mallinckrodt Pharmaceuticals CVS Caremark Corporation Walgreen Co. Walmart Stores Inc Rite Aid Corporation Actavis PLC your-feed-healthcare Source Type: news
Authors: Thulaseedaran NK, Kumar KGS, Kumar J, Geetha P, Jayachandran NV, Kamalasanan CG, Mathew S, Pv S Abstract During May 2018 there occurred an outbreak in Kerala, which started in Soopikkada Village, Changarothu Grama Panchayath in Perambra Taluk, Kozhikode district, of a febrile illness with altered sensorium and ARDS. The diagnosis was made from the second case that it is the dreaded nipah infection. Following that 18 cases tested positive for nipah virus infection of which 2 survived. Also there were four deaths with similar clinical picture but which occurred before the virus was identified. They were cons...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Tiwari SB Abstract Introduction: HIV AIDS epidemic currently in India is quite under control, the efforts of NACO and community at large has lead to this. The current prevalence of HIV among adults is around) 0.3%, the widespread prevention and control strategies are the main reason behind the same. HAART coverage has also increased significantly which has played a major role in not only controlling the epidemic but also in the change of clinical scenario and clinical affection in patients of HIV AIDS. The neurological complications arising in HIV patients, either due to opportunistic infections or due to ...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
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