Five-year outcomes of intravitreal ranibizumab for choroidal neovascularization in patients with pathologic myopia

Conclusion: Intravitreal ranibizumab provide a 5-year visual benefit in eyes with myopic CNV compared with the natural course. A lack of enlargement of the CNV-related macular atrophy, a better baseline BCVA, and a minimum number of IVR injections were associated with better visual outcomes.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research

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Conclusions: FCE are relatively frequently encountered morphologic features of elderly patients with ARMD, high myopia, and ARCA, and have a distinct clinical and imaging morphology which differs from classically described chorioretinal folds. The lesions may commonly be mistaken for pigment epithelial detachments on ophthalmoscopy, may be associated with CNV in fellow eyes, and have a characteristic SD-OCT appearance. PMID: 31687198 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Purpose: Evaluation of spherical component (SC), regular astigmatism (RA), and irregular astigmatism (IA, ie, Asymmetry and Irregularities) 3 years after small incision lenticule extraction (SMILE) and comparison to femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). Methods: Thirty-two eyes of 21 patients who underwent SMILE for myopia and astigmatism were compared with 32 eyes of 21 patients treated with FS-LASIK. Scheimpflug images were obtained preoperatively and 3 years postoperatively. Fourier analysis of keratometric-derived parameters (SC, RA, Asymmetry, and Irregularities) of the anterior, pos...
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Abstract Purpose: The purpose of this study was to investigate the relationship between aquaporin-1 (AQP-1) protein expression in the choroid and choroid thickness (CT) during the recovery of form-deprivation (FD) myopia in guinea pigs.Materials and Methods: Seventy-two guinea pigs were randomly assigned to the normal control (NC) group, FD 21 group (animals wore a latex facemask in the right eye for 21 days to induce FD myopia) and four recovery (REC) groups. Guinea pigs in the REC groups also wore the facemask for 21 days to induce myopia; then, the facemask was removed, and the eye was re-exposed to the normal ...
Source: Current Eye Research - Category: Opthalmology Authors: Tags: Curr Eye Res Source Type: research
Orthokeratology (Ortho-k) has been shown to be effective in slowing myopia progression [1 –7] and has become a popular myopia control treatment in many East Asian countries [8–10]. Cheung et al. [11] reported that ortho-k was the preferred optical myopia control intervention of Hong Kong parents for their children, because of the freedom from spectacle or contact lens wear during the daytime after stabilisation [11]. Hiraoka et al. [12] also found that good unaided vision contributed most to patients’ satisfaction.
Source: Contact Lens and Anterior Eye - Category: Opthalmology Authors: Source Type: research
CONCLUSION: Both aflibercept and ranibizumab provided a significant improvement in visual acuity and retinal thickness in patients with myopic choroidal neovascularization. Comparable functional and architectural results were achieved by both treatment modalities. PMID: 31690105 [PubMed - as supplied by publisher]
Source: European Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Eur J Ophthalmol Source Type: research
To report five cases of acute drug-induced angle closure and transient myopia with ciliochoroidal effusion and to analyze angiographic findings of these cases.
Source: BMC Ophthalmology - Category: Opthalmology Authors: Tags: Research article Source Type: research
Abstract Myopia is a complex, multifactorial condition influenced by genetic and environmental factors. Singapore has one of the world's highest myopia rates. The National Myopia Prevention Programme was started in 2001 with the goal of delaying the onset and progression of myopia through public education and vision screening. Public education targeting children, youth and key stakeholders (parents and teachers) focused on increasing awareness of myopia and its complications, and good eye care habits. Regular school-based vision screening for early detection/management and monitoring of myopia prevalence found tha...
Source: Singapore Medical Journal - Category: General Medicine Authors: Tags: Singapore Med J Source Type: research
Conclusions: The results of this meta-analysis suggested the rs524952 and rs634990 polymorphisms may have nothing to do with the development of HM. The present results must be confirmed with larger-scale studies in the future. PMID: 31673225 [PubMed - in process]
Source: Molecular Vision - Category: Molecular Biology Tags: Mol Vis Source Type: research
Rationale: Spherophakia is a rare diagnosis which is often associated with a shallow anterior chamber, angle-closure glaucoma, lens subluxation, and lenticular myopia. When cataracts occur with subluxation of the lens, vision is often markedly affected. This often presents surgeons with a unique challenge of maintaining good visual outcomes while minimizing potential complications. Patient concerns: A 48-year-old female was referred for ophthalmological assessment due to decreased vision in the left eye. In the left eye, the best-corrected visual acuity at distance was 20/125 with manifest refraction of −6.5D + ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Late IOL dislocation is becoming a more frequently occurring event after previously uncomplicated cataract surgery. Pseudoexfoliation, status post-vitrectomy, myopia, trauma, and uveitis are the most common causes, and these are at cumulative risk.
Source: Journal of Cataract and Refractive Surgery - Category: Opthalmology Authors: Tags: Consultation section: Cataract Source Type: research
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