Vitamin D treatment for chronic urticaria: a case report
ConclusionsIn some patients, vitamin D may have a role in the pathophysiology and treatment of chronic urticaria; however, the cost-effectiveness of routine laboratory screening in chronic urticaria is unknown.
Conditions: Urticaria; Vitamin D Deficiency Intervention: Drug: Vit D Sponsor: Postgraduate Institute of Medical Education and Research Enrolling by invitation
ConclusionCSU patients had significantly lower serum vitamin D levels than the controls in most studies. However, the results did not prove causation, and the mechanisms were not clearly explained. Despite the scarcity of available studies, this systematic review showed that a high dosage of vitamin D supplementation for 4 –12 weeks might help to decrease the disease activity in some CSU patients. Well-designed randomized placebo-controlled studies are needed to determine the cut-off levels of vitamin D for supplementation and treatment outcomes.
chronic urticaria (CU) is a complex disorder associated with a chronic systemic inflammation. This inflammation could be related with the release of adipokines with proinflammatory and anti-inflammatory properties. Vitamin D (VitD) deficiency has been associated with CU. The purpose of this study was to analyze the association between serum levels of VitD, leptin, and adiponectin with CU in Colombian Caribbean adults.
This study analyzed the association between polymorphisms of VDR SNPs and serum levels of vitamin D (VitD) with CSU in a Caribbean multi-ethnic adult patients sample.