Golgi phosphoprotein-3 promotes invasiveness of gastric cancer cells through the mTOR signalling pathway.

CONCLUSIONS: In conclusion, GOLPH3 increased in poorly-differentiated gastric cancer cells, activating the mTOR-70S6K/4EBP1-RhoA signalling pathway to promote the migration and metastasis of gastric cancer cells.
PMID: 31228964 [PubMed - in process]

Source: Clinical and Investigative Medicine - June 22, 2019 Category: Biomedical Science Authors: Liu J, Wei H, Lai L, Wang Y, Han X, Zhang Z Tags: Clin Invest Med Source Type: research