Effect of Gastric Acid Suppressants on Response to a Physical Activity Intervention and Major Mobility Disability in Older Adults: Results from the Lifestyle Interventions for Elders (LIFE) Study

ConclusionsCompared to non ‐users, participants using either PPIs or H2RAs had increased risk of MMD, pMMD, and injurious falls. It is not known if these effects are related to the individual pharmacology of each medication, reduced acid secretion, or the underlying disease state. Further study is required to determine caus ality.This article is protected by copyright. All rights reserved.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - June 22, 2019 Category: Drugs & Pharmacology Authors: Patrick J Squires, Marco Pahor, Todd M Manini, Joshua D Brown Tags: Original Research Article Source Type: research