Valproic acid potently inhibits interictal-like epileptiform activity in prefrontal cortex pyramidal neurons
This study shows that it is possible to evoke NMDA-dependent epileptiform activity in prefrontal cortex pyramidal neurons in vitro.We suggest that the prefrontal cortex is a good region for studying the influence of drugs on interictal epileptiform activity.Graphical abstract
Source: Neuroscience Letters - Category: Neuroscience Source Type: research