Births from embryos with highly elevated production of mitochondrial DNA

ConclusionsMeasurement of mtDNA copy number might not provide any advantage in embryo prioritization and could lead to a deselection of blastocysts that would result in healthy pregnancies and births. Furthermore, the quantification of mitochondrial functional output in a model of cellular stress might suggest that mitochondria are not clear targets for biomarker identification as it relates to blastocyst viability. Any suggested link between mtDNA production, mitochondria or their output with blastocyst transfer outcome requires further validation.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research