Changes in inflammatory protein and lipid mediator profiles persist after antitubercular treatment of pulmonary and extrapulmonary tuberculosis: A prospective cohort study.

CONCLUSION: Our findings describe systemic and durable changes in the concentrations of inflammatory cytokines and lipid mediators in both PTB and EPTB and emphasize the role of M. tuberculosis bacterial burden and site of disease in modulating patient immune biomarkers.
PMID: 31226436 [PubMed - as supplied by publisher]

Source: Cytokine - June 17, 2019 Category: Molecular Biology Authors: Vinhaes CL, Oliveira-de-Souza D, Silveira-Mattos PS, Nogueira B, Shi R, Wei W, Yuan X, Zhang G, Cai Y, Barry CE, Via LE, Fukutani KF, Andrade BB, Mayer-Barber KD Tags: Cytokine Source Type: research