Progress in research on paclitaxel and tumor immunotherapy.

This study summarizes the recent advances in our understanding of the sources, the anticancer mechanism, and the biosynthetic pathway of paclitaxel. With the advancement of biotechnology, improvements in endophytic fungal strains, and the use of recombination techniques and microbial fermentation engineering, the yield of extracted paclitaxel has increased significantly. Recently, paclitaxel has been found to play a large role in tumor immunity, and it has a great potential for use in many cancer treatments.
PMID: 31223315 [PubMed - in process]

Source: Cellular and Molecular Biology Letters - June 23, 2019 Category: Biochemistry Authors: Zhu L, Chen L Tags: Cell Mol Biol Lett Source Type: research