LncRNA GASL1 is downregulated in chronic heart failure and regulates cardiomyocyte apoptosis.

Conclusion: In conclusion, GASL1 was downregulated in CHF. GASL1 overexpression may improve CHF by inhibiting cardiomyocyte apoptosis through the inactivation of TGF-β1.
PMID: 31223316 [PubMed - in process]

Source: Cellular and Molecular Biology Letters - June 23, 2019 Category: Biochemistry Authors: Deng H, Ouyang W, Zhang L, Xiao X, Huang Z, Zhu W Tags: Cell Mol Biol Lett Source Type: research