5-Nitro-Thiophene-Thiosemicarbazone Derivatives Present Antitumor Activity Mediated by Apoptosis and DNA Intercalation.
CONCLUSION: Our findings highlight 5-nitro-thiophene-thiosemicarbazone derivatives, especially LNN-05, as a promising new class of compounds for further studies to provide new anticancer therapies.
PMID: 31223089 [PubMed - as supplied by publisher]
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Roque Marques KM, do Desterro MR, de Arruda SM, de-Araújo Neto LN, de Lima MDCA, de Almeida SMV, Silva ECDD, Aquino TM, Júnior EFDS, Júnior JXD, Silva MM, de A Dantas MD, C Santos JC, Figueiredo IM, Bazin MA, Marchand P, da Silva TG, Mendonça Junior F Tags: Curr Top Med Chem Source Type: research