The Cardiac Health and Assessment of Relationship Management and Sexuality Study: A Qualitative Inquiry of Patient, General Practitioner, and Cardiac Rehabilitation Staff Views on Sexual Assessment and Counseling for Cardiac Patients.

CONCLUSIONS:: Perspectives differed both across and within stakeholder groups about current services and the development of future services. A disconnect exists between the service that the professionals perceive they give and that experienced by patients. Sexual assessment and counseling should be addressed more explicitly, and patients should be empowered to seek individual assessment and counseling at a time that is appropriate for them. PMID: 23392524 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Nursing - Category: Nursing Authors: Tags: J Cardiovasc Nurs Source Type: research

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The inhibition of miR‑101a‑3p alleviates H/R injury in H9C2 cells by regulating the JAK2/STAT3 pathway. Mol Med Rep. 2019 Nov 05;: Authors: Liu J, Wang J, Ning Y, Chen F Abstract Hypoxia/reoxygenation (H/R) is used as an in vivo model of ischemia/reperfusion injury, and myocardial ischemia can lead to heart disease. Therefore, it is necessary to prevent myocardial H/R injury to avoid the risk of heart disease. The aim of the present study was to investigate whether inhibiting microRNA (miR)‑101a‑3p attenuated H9C2 cell H/R injury, apoptosis mechanisms and key target proteins. Cell viabilit...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Kai‑Xin‑San suppresses matrix metalloproteinases and myocardial apoptosis in rats with myocardial infarction and depression. Mol Med Rep. 2019 Nov 06;: Authors: Hu Y, Dong X, Zhang T, Ma H, Yang W, Wang Y, Liu P, Chen Y Abstract Depression is often triggered by prolonged exposure to psychosocial stressors and associated with coronary heart disease (CHD). Matrix metalloproteinases (MMPs) are involved in the pathogenesis of various emotional and cardiovascular disorders. The purpose of this study was to investigate whether Kai‑Xin‑San (KXS), which may terminate the signaling of MMPs, exerts antid...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Interleukin‑37 is increased in peripheral blood mononuclear cells of coronary heart disease patients and inhibits the inflammatory reaction. Mol Med Rep. 2019 Nov 06;: Authors: Li H, Shen C, Chen B, Du J, Peng B, Wang W, Chi F, Dong X, Huang Z, Yang C Abstract It has been universally acknowledged that interleukin‑37 (IL‑37) has an immunosuppressive effect on various inflammatory disorders. However, whether IL‑37 participates in the acute inflammation associated with coronary heart disease (CHD) has not yet been clarified. In the present study, the association between the serum levels of IL‑37...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Baumbach A, Dudek D, Baumgartner H, Windecker S, Haude M Abstract The field of valve intervention is rapidly changing. Clinical practice guidelines are based on evidence and practical clinical experience. The randomised trials considered for the guideline recommendations regarding indications for TAVI cover the high-risk and intermediate-risk subgroups of patients. With new evidence for low-risk patients, consideration has to be given to discussing TAVI as the default strategy in the majority of patients. This is a paradigm shift from the established practice. More than ever, the patient will be at the cen...
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Authors: Overtchouk P, Vahanian A, Modine T PMID: 31746747 [PubMed - in process]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Authors: Tamburino C, Piazza N, Baumbach A, Windecker S, Maisano F, Prendergast BD PMID: 31746744 [PubMed - in process]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Conclusions Aging leads to a progressive decrease in androgen production that, in turn, leads to the development of LOH, defined by significant low T serum levels (in the lowest quartile) in the presence of signs and symptoms of hypogonadism (51). LOH could be due to both testicular and hypothalamic-pituitary dysfunction (32), and ED is one of its main symptoms. ED in LOH is linked to increased oxidative stress, subclinical inflammation, and subsequent endothelial dysfunction (101). In elderly men, it has been shown that LOH is also linked to lower cAMP pool and to an alteration of the cGMP signaling pathway. PDE5 gene l...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
POSTMENOPAUSAL HEALTH INTERVENTIONS: TIME TO MOVE ON FROM THE WOMEN'S HEALTH INITIATIVE? Ageing Res Rev. 2018 Oct 21;: Authors: Thaung Zaw JJ, Howe PRC, Wong RHX Abstract Menopause is a critical period during which, without timely interventions, increased risks of cardiovascular and metabolic diseases, osteoporosis, sexual dysfunction and premature cognitive decline will contribute to diminished quality-of-life in women. Hormone therapy (HT) used to be the standard of care for managing vasomotor symptoms and prevention of chronic diseases until publication of the Women's Health Initiative (WHI) in 200...
Source: Ageing Research Reviews - Category: Genetics & Stem Cells Authors: Tags: Ageing Res Rev Source Type: research
Gynecologists performing hysterectomy for benign disease must universally counsel women about ovarian management. The beneficial effect of elective bilateral salpingo-oophorectomy (BSO) on incident ovarian and breast cancer and elimination of need for subsequent adnexal surgery must be weighed against the risks of ovarian hormone withdrawal. Ovarian conservation rates have increased significantly over the past 15  years. In postmenopausal women, however, BSO can reduce ovarian and breast cancer rates without an adverse impact on coronary heart disease, sexual dysfunction, hip fractures, or cognitive function.
Source: Obstetrics and Gynecology Clinics - Category: OBGYN Authors: Source Type: research
Is this new drug flianserin really the "female Viagra," or is it just a drug that empowers women to talk about gender discrimination? The FDA advisory committee has recently recommended approval of the still-experimental drug flibanserin (also known as Addyi) to help sexual dysfunction in women. After this action has generated many opinions about achieving gender equality for women, getting the FDA to approve a "female Viagra," and even prompted arguments that the FDA has been practicing gender discrimination, let's look at some of the facts and what it means for each of us today. An illness, hypoactiv...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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