Molecular senescence is associated with white matter microstructural damage in late-life depression

Late-Life Depression (LLD) is common and associated with cognitive impairment and higher risk for dementia.1,2 The mediators of risk are not well understood, but probably involve the interaction of biological mechanisms related to aging processes, like inflammatory activation, loss of proteostasis control, increased tissue remodeling markers and reduced neurotrophic support.3
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Brief Report Source Type: research

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(Natural News) Antidepressants and antihistamines are among the most common types of medications people take, and they belong to a class of drugs known as anticholinergics. These drugs can treat a variety of health problems, including COPD, asthma, depression, dizziness, gastrointestinal problems, overactive bladder, and the symptoms of Parkinson’s. Although they can be effective, a...
Source: - Category: Consumer Health News Source Type: news
CONCLUSIONS: CES-D is a valid and reliable scale for detecting caregiver depression in dementia. It has added utility, beyond that of a caregiver burden scale, in identifying a subgroup of caregivers with depression but not burden. However, two subscales (Positive affect and Interpersonal problems) may require caution in interpretation among non-Caucasian caregivers. PMID: 31307034 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Frequent use of sleep medications appears to be associated with increased long-term risk of dementia, particularly among older white adults, according to research presented at the Alzheimer's Association International Conference in Los Angeles this week.“Based on our findings, we recommend that clinicians make more effort to be aware of their patients’ sleep problems including use of sleep aids,” said lead study author Yue Leng, Ph.D., of the University of California, San Francisco, in apress release.Leng and colleagues studied 3,068 black and white community-dwelling older adults aged 70 to 79 years who ...
Source: Psychiatr News - Category: Psychiatry Tags: Association International Conference dementia Los Angeles older white adults sleep medications Source Type: research
CONCLUSION: bvFTD is an important differential diagnosis to consider when patients present with atypical psychiatric symptoms. PMID: 31310153 [PubMed - as supplied by publisher]
Source: Australasian Psychiatry - Category: Psychiatry Authors: Tags: Australas Psychiatry Source Type: research
...We feel like we're letting everyone down, especially if we have children as well as elders to care for, and perhaps a spouse we don’t want to ignore. We try. We try so hard. Yet, it seems like we are spread so thin that, in our view at least, our loved ones all get shortchanged. This can, indeed, be depressing. Read more on HealthCentral to learn more about caregivers and depression: Carol Bradley Bursack is the Candid Caregiver MedicareFAQ – Medicare Resource Center Support a caregiver or jump-start discussion in support groups with real stories - for bulk orders of Minding Our Elders e-mail Carol ...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
LOS ANGELES (AP) — Scientists are closing in on a long-sought goal — a blood test to screen people for possible signs of Alzheimer’s disease and other forms of dementia. On Monday at the Alzheimer’s Association International Conference, half a dozen research groups gave new results on various experimental tests, including one that seems 88% accurate at indicating Alzheimer’s risk. Doctors are hoping for something to use during routine exams, where most dementia symptoms are evaluated, to gauge who needs more extensive testing. Current tools such as brain scans and spinal fluid tests are too ex...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Alzheimer's Disease Dementia Source Type: news
CONCLUSION: Caregiving of PwD affects subjective sleep quality as well as daytime sleepiness of caregiving relatives. Both dimensions of sleep quality were associated with several personal and caregiving related variables. Chronic poor sleep quality is a high-risk factor for psychological and physical health problems and should be considered in further research and development of interventions for caregiving relatives of PwD. PMID: 31309276 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Gerontologie und Geriatrie - Category: Geriatrics Authors: Tags: Z Gerontol Geriatr Source Type: research
This study investigated the feasibility of a cognitive behavioral therapy (CBT) program for a female patient with mild cognitive impairment (MCI), depression, and anxiety, to improve her mood and quality of life. The program comprised of eight 30-minute weekly sessions with interventions such as behavioral activation, relaxation, and cognitive reconstruction, in which the patient's caregiver also participated. An assessment evaluating the patient's condition were conducted before and immediately after the intervention. After 3 and 12 months, the caregiver reported the patient's behavioral and psychological symptoms using s...
Source: Journal of Nippon Medical School - Category: Universities & Medical Training Authors: Tags: J Nippon Med Sch Source Type: research
“In my case, symptoms began to appear when I was only 57. In fact, the doctors believe early-onset Alzheimer’s has a strong genetic predictor, and that it may have been progressing for some years before I was diagnosed.” – Pat Summitt  Anyone who’s gone through the experience of a loved one developing Alzheimer’s disease and progressively deteriorating to a shell of their former selves knows how devastating this brain disease is for both patient and those who love and care for him or her.  Memory Performance Changes May Show Up in 20s with Family History of Alzheimer’s St...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Aging Alzheimer's Memory and Perception Alzheimer's disease Dementia Source Type: blogs
There hasn’t been much good news about Alzheimer’s lately, between the March announcement by Biogen and Esai that a promising trial of a potential drug treatment failed, and the July decision by Novartis and Amgen to stop their study of another class of therapies for the neurodegenerative disease. But in a pair of studies presented at the annual Alzheimer’s Association International Conference on July 14, researchers reported encouraging results from studies of non-drug approaches. In one, scientists led by Dr. Klodian Dhana at Rush University Medical Center in Chicago followed nearly 2,500 people for alm...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Alzheimer's Brain embargoed study Source Type: news
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