METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

METTL3 is known to be involved in all stages in the life cycle of RNA. It affects the tumor formation by the regulation the m6A modification in the mRNAs of critical oncogenes or tumor suppressors. In bladder ...

Source: Molecular Cancer - June 22, 2019 Category: Cancer & Oncology Authors: Jie Han, Jing-zi Wang, Xiao Yang, Hao Yu, Rui Zhou, Hong-Cheng Lu, Wen-Bo Yuan, Jian-chen Lu, Zi-jian Zhou, Qiang Lu, Ji-Fu Wei and Haiwei Yang Tags: Research Source Type: research