Setup strategies and uncertainties in esophageal radiotherapy based on detailed intra- and interfractional tumor motion mapping
Discouraging overall survival rates have been the reality for esophageal cancer patients, although multimodality treatment combining chemo-radiotherapy (RT) with surgery has lately significantly increased the survival rate [1 –4]. Large target volumes are often irradiated due to extensive tumor burden, the risk of subclinical spread along the esophagus and involvement of regional lymph nodes [5–6]. This results in increased risk of severe, potentially lethal normal tissue toxicities for the esophagus, heart and lungs [7–11].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Lone Hoffmann, Per R. Poulsen, Thomas Ravkilde, Jenny Bertholet, Iryna Kruhlikava, Bj ørn L. Helbo, Mai L. Schmidt, Marianne Nordsmark Tags: Original Article Source Type: research
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