Setup strategies and uncertainties in esophageal radiotherapy based on detailed intra- and interfractional tumor motion mapping

Discouraging overall survival rates have been the reality for esophageal cancer patients, although multimodality treatment combining chemo-radiotherapy (RT) with surgery has lately significantly increased the survival rate [1 –4]. Large target volumes are often irradiated due to extensive tumor burden, the risk of subclinical spread along the esophagus and involvement of regional lymph nodes [5–6]. This results in increased risk of severe, potentially lethal normal tissue toxicities for the esophagus, heart and lungs [7–11].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research