Newly identified natural protein blocks HIV, other deadly viruses
(University of California - Los Angeles Health Sciences) A team of UCLA-led researchers has identified a protein with broad virus-fighting properties that potentially could be used as a weapon against deadly human pathogenic viruses such as HIV, Ebola, Rift Valley Fever, Nipah and others designated "priority pathogens" for national biosecurity purposes by the National Institute of Allergy and Infectious Disease.
CONCLUSION: Taken together, the results of this investigation revealed the part of molecular and immunological mechanisms of drug Mannuronic acid (M2000) in treatment of RA, based on chemokine ligands and receptors mediated processes. PMID: 31729947 [PubMed - as supplied by publisher]
CONCLUSIONS: Short-term changes in exposure and subsequently in the spectrum of major contact allergens can best be illustrated by clinical surveillance based on routinely collected data and, if needed, preventive measures can be initiated. In addition to time trend analyses, subgroup analyses may offer important clues regarding the identification of sensitizing and eliciting exposures, respectively. PMID: 31728552 [PubMed - as supplied by publisher]
The objective of this study was to test the hypothesis that comorbid type 2 immune diseases confer protection against morbidity and mortality due to acute infection. Design: Retrospective cohort study of patients hospitalized with an acute infection between November 2008 and January 2016 using electronic health record data. Setting: Single tertiary-care academic medical center. Patients: Admissions to the hospital through the emergency department with likely infection at the time of admission who may or may not have had a type 2 immune-mediated disease, defined as asthma, allergic rhinitis, atopic dermatitis, or f...
CONCLUSIONS: Children in ECEC benefit from cooks' commitment to providing nutritious foods, however, the requirements to extend their role to respond to increasing demands without relevant system-level support and training puts the children at risk of not being exposed to health-promoting menus and possible errors in providing dietary modifications. ECEC cooks urgently need access to system-level support and training. SO WHAT: Understanding and addressing the barriers experienced by cooks and the complexity of factors that inform their food-related decision-making will sustain the implementation of effective, healthy e...
Contributors : Seblewongel Asrat ; Navneet Kaur ; Xia Liu ; Li-Hong Ben ; Daisuke Kajimura ; Andrew J Murphy ; Matthew A Sleeman ; Andre Limnander ; Jamie M OrengoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusSummary: Long-lived IgE plasma cells reside in the bone marrow of allergic mice and atopic humans, confer IgE serological memory and produce allergen-specific IgE that can drive anaphylaxis.Abstract: Immunoglobulin E (IgE) plays an important role in allergic diseases. Nevertheless, the source of IgE serological memory remains controversial. We re-examined the mechanism of serol...
[RESPIRATORY TRACT INFECTION AND ALLERGY]. Arerugi. 2019;68(9):1121-1125 Authors: Tsutsumi H PMID: 31723108 [PubMed - in process]
[PREVENTION OF FOOD ALLERGY]. Arerugi. 2019;68(9):1115-1120 Authors: Ohya Y PMID: 31723107 [PubMed - in process]
[NON-IGE MEDIATED GASTROINTESTINAL FOOD ALLERGY AND EOSINOPHILIC GASTROINTESTINAL DISORDERS]. Arerugi. 2019;68(9):1102-1109 Authors: Yamada Y PMID: 31723105 [PubMed - in process]
[IMMUNOLOGICAL MECHANISMS OF DEVELOPMENT, TOLERANCE AND PREVENTION OF FOOD ALLERGY]. Arerugi. 2019;68(9):1089-1094 Authors: Ohshima Y PMID: 31723103 [PubMed - in process]