Metal free visible light photocatalytic carbon nitride quantum dots as efficient antibacterial agents: An insight study

Publication date: November 2019Source: Carbon, Volume 152Author(s): Pranjali Yadav, S.T. Nishanthi, Bhagyesh Purohit, Asifkhan Shanavas, Kamalakannan KailasamAbstractGraphitic carbon nitride (g-CN, commonly called as g-C3N4) quantum dots exhibiting excellent photoluminescence behaviour is explored as metal-free visible light photocatalytic antibacterial agents. The g-CNQDs were synthesized by two-step thermal polymerization and selective dialysis approach yielding particle size in the range of 2–7 nm with a large specific surface area of 264 m2/g. The fluorescent g-CNQDs could efficiently generate superoxide and hydroxyl radicals under visible light irradiation, inhibiting∼99% of Gram negative E.coli and ∼90% of Gram positive S.aureus at a concentration of 0.1 mg/mL. A strong correlation between the TEM, SEM and confocal microscopic analysis is observed demonstrating that g-CNQDs cause light induced photo toxicity. This toxicity is caused by the physical interaction (between the QDs and cells) and due to the generation of ROS in presence of light. The g-CNQDs were found to be non-toxic to fibroblast cells up to a concentration of 3.2 mg/mL. A comprehensive comparison of g-CNQDs with bulk non-porous g-CN, mesoporous CN, silver loaded mesoporous CN and bare silver nanoparticles indicated them to be promising photo induced bactericidal material.Graphical abstract
Source: Carbon - Category: Materials Science Source Type: research

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Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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Publication date: Available online 14 June 2019Source: CarbonAuthor(s): Pranjali Yadav, S.T. Nishanthi, Bhagyesh Purohit, Asifkhan Shanavas, Kamalakannan KailasamAbstractGraphitic carbon nitride (g-CN, commonly called as g-C3N4) quantum dots exhibiting excellent photoluminescence behaviour is explored as metal-free visible light photocatalytic antibacterial agents. The g-CNQDs were synthesized by two-step thermal polymerization and selective dialysis approach yielding particle size in the range of 2–7 nm with a large specific surface area of 264 m2/g. The fluorescent g-CNQDs could efficiently generate superoxide ...
Source: Carbon - Category: Materials Science Source Type: research
CONCLUSION: Gram-positive cocci are still the primary pathogen of PDAP cases in our center, but demonstrate a high resistance to first-generation cephalosporin, which is the suggested treatment per International Society for Peritoneal Dialysis 2016 Peritonitis Recommendations. Therefore, an individualized treatment based on the distribution of pathogens and drug resistance in different centers is more conducive to improve the cure rate of PDAP.
. PMID: 31131821 [PubMed - as supplied by publisher]
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Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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Source: Peritoneal Dialysis International - Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research
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