Synthetic bacteria for therapeutics: applications of synthetic systems.

Synthetic bacteria for therapeutics: applications of synthetic systems.
J Microbiol Biotechnol. 2019 Jun 04;:
Authors: Vo PNL, Lee HM, Na D
Abstract
Synthetic biology builds programmed biological systems for a wide range of purposes such as improving human health, remedying the environment, and boosting the production of valuable chemical substances. In recent years, the rapid development of synthetic biology has enabled synthetic bacterium-based diagnoses and therapeutics superior to traditional methodologies by engaging bacterial sensing of and response to environmental signals inherent in these complex biological systems. Biosynthetic systems have opened a new avenue of disease diagnosis and treatment. In this review, we introduce designed synthetic bacterial systems acting as living therapeutics in the diagnosis and treatment of several diseases. We also discuss the safety and robustness of genetically modified synthetic bacteria inside the human body.
PMID: 31216840 [PubMed - as supplied by publisher]

Source: Journal of Microbiology and Biotechnology - June 3, 2019 Category: Biotechnology Authors: Vo PNL, Lee HM, Na D Tags: J Microbiol Biotechnol Source Type: research