Targeted metabolomics to investigate antimicrobial activity of itaconic acid in marine molluscs

ConclusionsWe reported on the production of ITA in different tissues ofP. canaliculus mussels challenged with a marine pathogen which confirmed ITA as an antimicrobial metabolite. The findings revealed insights into the biosynthesis of ITA and suggests its role in antimicrobial and anti-inflammatory activities in the innate immune system. This study also provided insights into the innate immune system of bivalves and highlighted the potential use of ITA as a biomarker for shellfish health assessment in aquaculture.

Source: Metabolomics - June 21, 2019 Category: Biology Source Type: research